产品货号：
Z37213
中文名称：
Hu CD14 Purified抗体
英文名称：
Anti-Hu CD14 Purified Antibody (Clone#B-A8)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu CD14 Purified Antibody (Clone#B-A8) |
| 指标别名 | CD14;CD14 molecule |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IHC,FCM |
| 基因名称 | CD14 |
| 克隆号 | B-A8 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human monocytes.The mouse monoclonal antibody B-A8 reacts with CD14,a 53～55kDa GPI (glycosylphosphatidylinositol)-linked extracellular membrane glycoprotein expressed on the surface of monocytes,macrophages and weakly on granulocytes;also expressed by most tissue macrophages. |
| 计算分子量 | 40kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods). |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD14 is a 55kDa GPI-anchored glycoprotein,constitutively expressed on the surface of mature monocytes,macrophages,and neutrophils,where it serves as a multifunctional lipopolysaccharide receptor.It is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form.CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP),an acute phase serum protein.The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles.CD14 affects allergic,inflammatory and infectious processes. |
| Uniprot ID | P08571 |
| 基因名全称 | CD14 molecule |
| 蛋白名全称 | Monocyte differentiation antigen CD14 |
| 推荐稀释比 | ELISA:The antibody B-A8 has been tested as the capture antibody in a sandwich ELISA for analysis of human CD14 in combination with antibody MEM-18 (cat.no.1B-212-C100).Flow cytometry:recommended dilution:1μg/mL;Immunohistochemistry (paraffin sections):recommended dilution:2～10μg/mL,positive tissue:PML brain sections;positive staining on human PML brain sections was mainly observed on monocytes in the lumenal side of brain blood vessels,and on some perivascular cells adjacent to medium-sized vessels.Heat retrieval of antigen is recommeded. |
相关搜索：Hu CD14 Purified抗体，Hu CD14 Purified单抗，Anti-Hu CD14 Purified Antibody (Clone#B-A8)